University of Massachusetts researching techniques for individual genes for inactivation—a technique with broad potential implications for both basic science research and human disease. Two scientific teams at UMMS, one led by Scot A. Wolfe, PhD, an assistant professor in the Program in Gene Function & Expression and the Department of Biochemistry & Molecular Pharmacology, and the other by Nathan D. Lawson, PhD, an associate professor in the Program in Gene Function and Expression and the Program in Molecular Medicine, working with a small fish—the zebrafish—commonly used as a model organism in biomedical research, developed a method to create and deliver a tailor-made “restriction enzyme” that inactivates a specific gene in a zebrafish embryo. The paper, “Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases” appears as an Advance Online Publication of the journal Nature Biotechnology.
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kimrennin
Massachusetts Drug Addiction